Thiazolide compounds for treating viral infections
AssigneeRomark Laboratories L.C.
InventorsJean-Francois Rossignol, Maria Gabriella Santoro
Life of this patent
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Abstract
Thiazolide compounds, such as nitazoxanide and/or tizoxanide, may be used against viruses belonging to the Picornaviridae family or the Paramyxoviridae family.
Claims24
A method of treating a disease or condition caused by or associated with a virus belonging to the Paramyxoviridae family, comprising administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising at least one of nitazoxanide or tizoxanide or a pharmaceutically acceptable salt thereof, wherein the effective amount is an amount which blocks in the subject the maturation of the fusion (F) glycoprotein of the virus.
A method of treating a disease or condition caused by or associated with a virus belonging to the Henipavirus genus, comprising administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising at least one of nitazoxanide or tizoxanide or a pharmaceutically acceptable salt thereof,
A method of treating a disease or condition caused by or associated with a virus belonging to the Picornaviridae family, comprising administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising at least one of nitazoxanide or tizoxanide or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.