Methods for the treatment of rosacea
AssigneeSol-Gel Technologies Ltd.
InventorsHanan SERTCHOOK, Ofer TOLEDANO, Haim BAR-SIMANTOV
Life of this patent
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Abstract
The present invention relates to pharmaceutical compositions for topical use (including also dermatological compositions), for treating skin conditions and afflictions, such as rosacea and symptoms and conditions associated there from.
Claims21
1-20. (canceled)
A method of treating rosacea in a patient in need thereof, comprising:
- topically administering to a rosacea affected skin surface of said patient a composition comprising as a sole pharmaceutical active agent 1-10% by weight benzoyl peroxide in solid form,
- wherein said composition has a benzoyl peroxide dissolution rate of less than about 80% weight/h as measured in a medium of a 55%:45% mixture of water and acetonitrile at ambient temperature.
A method of treating rosacea in a patient in need thereof, comprising:
- topically administering to a rosacea affected skin surface of said patient a composition comprising as a sole pharmaceutical active agent 1-10% by weight benzoyl peroxide in solid form,
- wherein said composition is administered once daily over 12 weeks and provides more than 20% success rate of treatment, the success rate being a 2-grade improvement over baseline in an Investigator Global Assessment (IGA).
A method of treating rosacea in a patient in need thereof, comprising:
- topically administering to a rosacea affected skin surface of said patient a composition comprising as a sole pharmaceutical active agent 1-10% by weight benzoyl peroxide in solid form,
- wherein said treatment has an adverse events values of not more than 40%.
The method of claim 38, wherein said composition has a benzoyl peroxide dissolution rate of less than about 80% weight/h as measured in a medium of a 55%:45% mixture of water and acetonitrile at ambient temperature.
Dependencies are inferred from the claim text.