Gastric reflux resistant dosage forms

A method for manufacturing an oral gastric resistant soft capsule dosage form, the method comprising:

• preparing a gell mass composition consisting of:
• about 25% to about 40% by weight gelatin, about 8% to about 30% by weight of one or more plasticizers, about 2% to about 5% by weight pectin, and less than 1% by weight of a gelling agent consisting of calcium salts or magnesium salts;
• casting the gel mass into films or ribbons;
• and
• forming a gastric resistant soft capsule encapsulating a fill material using rotary die encapsulation.

A method for manufacturing an oral gastric resistant soft capsule dosage form, the method comprising:

• preparing a gell mass composition consisting of:
• about 25% to about 40% by weight gelatin, about 8% to about 30% by weight of one or more plasticizers, about 2% to about 5% by weight pectin, and less than 1% by weight of a gelling agent consisting of calcium salts or magnesium salts;
• casting the gel mass into films or ribbons;
• and
• forming a gastric resistant soft capsule using rotary die encapsulation encapsulating a fill material comprising one or more pharmaceutically active agents or nutritionals and optionally one or more pharmaceutically acceptable excipients.