Method for manufacturing medicated chewing gum without cooling

A method for manufacturing chewing gum including at least one therapeutically active ingredient, comprising the steps of:

• placing one or more gum base(s) in a container with a sugar in an oven and heating said container until said gum base(s) melts to an internally measured temperature between 140-160 deg F.;
• mixing in a commercial mixer one or more active ingredient(s), sugar(s), and flavorings within a range of from 3 to 7 minutes;
• adding the melted gum base into the mixer and mixing within a range of from 2 to 6 minutes until a homogeneous mass is produced;
• conditioning said homogenous mass for at least 6 hours at a temperature not greater than 75 deg F. and 60% relative humidity;
• milling the dried mass into particulates at room temperature using a mesh screen of appropriate particle size ranging between 0.10 inch to 0.30 inch;
• mixing the particulates with lubricants in an orbital or planetary mixer within a range of from 2 to 4 minutes;
• and
• tableting the powder by a tablet press.

A process for manufacturing chewing gum containing a therapeutically-active ingredient, comprising:

• a first step of obtaining a quantity of a gum base;
• a second step of heating the gum base in an oven to an elevated temperature;
• a third step of obtaining one or more active ingredients and mixing said active ingredient(s) together in a mixer;
• a fourth step adding said heated gum base into the mixer while said elevated temperature exceeds a temperature of the mixer;
• a fifth step of mixing said combined gum base and active ingredient(s) in a mixer;
• and
• a sixth step of granulating said mixed gum base and active ingredient(s) by continuing said fifth step during cooling of said mixed gum base/active ingredients until said combined gum base and active ingredient(s) form granules;
• whereby said process avoids exposure of said granulated gum base and active ingredient(s) to excessive heat, cold and excess milling to thereby sustain efficacy of said one or more active ingredients.

A process for manufacturing chewing gum containing at least one therapeutically-active ingredient, comprising:

• obtaining a quantity of a gum base;
• obtaining one or more active ingredients;
• obtaining one or more sweeteners;
• obtaining one or more flavorings;
• combining said one or more active ingredients, one or more sweeteners, and one or more flavorings together in a mixer and mixing;
• heating the gum base to an elevated temperature;
• adding said heated gum base into the mixer while said elevated temperature exceeds a temperature of the mixer and mixing into a blended mass;
• removing said blended mass from the mixer and separating said blended mass into a plurality of trays;
• conditioning said blended mass in said trays at room temperature;
• removing said dried mass from said trays and milling said dried mass into a particulate powder at room temperature;
• adding said one or more active ingredients to said particulate powder and mixing;
• placing said mixed particulate powder and one or more active ingredients into a tablet press and tableting into tablets;
• whereby said process avoids exposure of said active ingredient(s) to excessive heat, cold and excess milling to thereby sustain efficacy of said one or more active ingredients.