Peptides and Their Use in the Treatment of Skin
AssigneeAvon Products, Inc.
InventorsJolanta Idkowiak-Baldys, John W. Lyga, Uma Santhanam
Life of this patent
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Abstract
Provided are methods of diminishing the signs of aging and/or improving the health of human integuments, such as skin, and compositions comprising peptides useful therefor. The compositions according to the invention comprise a peptide comprising the sequence QILSKLRL (SEQ ID NO: 1) or a derivative, or a 3-5 amino acid fragment thereof, in a topically acceptable vehicle.
Claims20
A method for improving the health and/or appearance of human skin affected by dermatological signs of aging comprising topically applying to an area of skin in need thereof a composition comprising, in a topically acceptable vehicle, an effective amount of a peptide comprising the sequence QILSKLRL (SEQ ID NO:
- 1), QIL (SEQ ID NO:
- 2), ILS (SEQ ID NO:
- 3), LSK (SEQ ID NO:
- 4), SKL (SEQ ID NO:
- 5), KLR (SEQ ID NO:
- 6), LRL (SEQ ID NO:
- 7), QILS (SEQ ID NO:
- 8), ILSK (SEQ ID NO:
- 9), LSKL (SEQ ID NO:
- 10), SKLR (SEQ ID NO:
- 11), KLRL (SEQ ID NO:
- 12), QILSK (SEQ ID NO:
- 13), ILSKL (SEQ ID NO:
- 14), LSKLR (SEQ ID NO:
- 15), or SKLRL (SEQ ID NO:
- 16), for a time sufficient to improve the appearance and/or health of said skin.
A composition comprising an effective amount of a peptide comprising the sequence QILSKLRL (SEQ ID NO:
- 1), QIL (SEQ ID NO:
- 2), ILS (SEQ ID NO:
- 3), LSK (SEQ ID NO:
- 4), SKL (SEQ ID NO:
- 5), KLR (SEQ ID NO:
- 6), LRL (SEQ ID NO:
- 7), QILS (SEQ ID NO:
- 8), ILSK (SEQ ID NO:
- 9), LSKL (SEQ ID NO:
- 10), SKLR (SEQ ID NO:
- 11), KLRL (SEQ ID NO:
- 12), QILSK (SEQ ID NO:
- 13), ILSKL (SEQ ID NO:
- 14), LSKLR (SEQ ID NO:
- 15), or SKLRL (SEQ ID NO:
- 16) and a topically acceptable vehicle.
Dependencies are inferred from the claim text.