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US 2017/0281409 A1Published application
Drug eluting ocular implant
AssigneeDose Medical Corporation
InventorsDavid S. Haffner, Kenneth M. Curry, Harold A. Heitzmann, David Applegate
Life of this patent
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Abstract
Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.
Claims1
A drug delivery ocular implant comprising
- an outer shell that is substantially impermeable to ocular fluids and has one or more orifices therein, said shell being shaped to define an interior lumen;
- a drug positioned within the interior lumen near the distal end of the shell,
- one or more coatings positioned on the interior surface of the shell, the outer surface of the shell, and/or enveloping the drug positioned within the interior lumen,
- a barrier placed within the interior lumen and proximal to the drug to limit anterior elution of the drug wherein the outer shell is substantially impermeable to the drug, wherein at least one of the coatings at least partially define the release rate of the drug, and
- wherein the implant is dimensioned such that the distal end of the implant is positioned in the suprachoroidal space and the proximal end of the implant is positioned fully within the eye.
2 more elements
Dependencies are inferred from the claim text.