Endoluminal prosthetic devices having fluid-absorbable compositions for repair of a vascular tissue defect

A prosthesis having a compressed configuration for delivery within a vasculature and a radially-expanded configuration for deployment within a target blood vessel in a patient, the prosthesis comprising:

• a tubular body having
• a first end and a second end, the first end having an anchoring structure to engage an inner wall of the target blood vessel in the radially-expanded configuration;
• and
• an elongated mid-portion between the first and second ends and including a channel formed in a wall thereof, wherein the channel is at least partially oriented circumferentially about the tubular body;
• and
• a fluid-absorbable composition deposited within the channel, the fluid-absorbable composition having a first volume when the prosthesis is in the compressed configuration and configured to swell to a second volume within the channel upon deployment of the prosthesis within the target blood vessel to thereby transition at least the elongated mid-portion into the radially-expanded configuration.