Image Registration Fiducials

A computing apparatus, comprising:

• a memory with computer executable instructions;
• and
• a processor configured to execute the computer executable instructions, wherein the processor, in response to executing the computer executable instructions:
• identifies a set of tissue fiducial markers in first imaging data based on a set measurement points for anatomical tissue of interest in the first imaging data;
• and
• registers the first imaging data with second imaging data based on the a set of tissue fiducial markers.

A computer readable storage medium encoded with computer executable instructions, which, when executed by a processor, causes the processor to:

• acquire an image of a tissue of interest;
• identify a plurality of pairs of points on the tissue of interest for a plurality of distances measurement, one between each pair of the plurality of pairs of points;
• identify a set of fiducial markers from at least two pairs of the plurality of pairs of points;
• acquire a reference volume of imaging data;
• and
• register the image with the volume, utilizing the set of fiducial markers as constraints on the registration.