Alert management for physiological event detection

A system for managing alerts associated with a target physiological event in a subject, the system comprising:

• a physiological sensor circuit including a sense amplifier circuit to sense a physiological signal;
• a signal processor circuit configured to generate a signal metric trend from the sensed physiological signal;
• an alert management circuit coupled to the signal processor circuit, the alert management circuit including:
• a comparator circuit to detect from the signal metric trend (1) one or more alert onsets using an onset threshold and (2) one or more corresponding alert terminations using a reset threshold;
• an alert generator circuit to issue one or more alerts corresponding to the detected one or more alert onsets and one or more alert terminations;
• and
• a parameter adjuster circuit to iteratively adjust the onset or reset threshold, including:
• when the one or more alerts fail to satisfy a specified alert characteristic, adjust the onset or reset threshold until the one or more alerts corresponding to the adjusted onset or reset threshold satisfy the specified alert characteristic;
• and
• when the one or more alerts satisfy the specified alert characteristic, determine target onset and reset thresholds for presenting to a user or a process, and
• a user interface for generating a human-perceptible presentation of the one or more alerts.