Multi-disease patient management

A system for identifying a patient's risk of developing a future worsening pulmonary disease, the system comprising:

• sensor circuits including a first sense amplifier circuit to sense a first physiological signal, a second sense amplifier circuit to sense a second physiological signal, and a third sense amplifier circuit to sense a third physiological signal;
• a signal processor circuit including filter circuits to generate a first signal metric from the first physiological signal, a second signal metric from the second physiological signal, and a third signal metric from the second physiological signal;
• a risk stratifier circuit coupled to the signal processor circuit, the risk stratifier circuit configured to:
• generate a primary pulmonary risk indication using at least the first signal metric;
• generate a secondary pulmonary risk indication using at least the second signal metric modulated by the third signal metrics, the modulation including multiplying the second signal metric by the third signal metric, or sampling the second signal metric conditional upon the third signal metric satisfying a specified condition;
• an output circuit configured to provide the composite cardiac risk indication to a clinician or a process.

A method for monitoring health status of a patient via a monitoring system, the method comprising:

• sensing one or more physiological signals;
• generating a first risk indication of the patient developing a first disease and a second risk indication of the patient developing a different second disease;
• detecting the first and second diseases from the one or more physiological signals;
• computing a composite health status indicator using the detections of the first and second diseases and the first and second risk indications;
• and
• generating a human-perceptible presentation of the composite health status indicator.