Capsule device and methodology for discovery of gut microbe roles in diseases with origin in gut

A method for diagnosing or treating disease associated with a gut or intestinal tract using a capsule device, comprising:

• providing a capsule device configured to be swallowed and passed through the intestinal tract of the patient, wherein the capsule comprises:
• a housing defining an opening adapted to allow at least one of sample matter, substances or small devices to pass into and out of the housing, wherein the shape of the device and housing are of a capsule type shape,
• at least one of a motor and actuator within the housing or an onboard autonomous and telemeter controlled circuitry, and
• at least one belt disposed within the housing and defining a plurality of indentations, each of the indentations having a volume configured to perform at least one of collecting and dispensing samples of matter,
• wherein the housing further comprises at least one of a substance or small device;
• actuating the control of the device so that the housing presents an opening;
• deploying the at least one of substance or small device when the device is actuated.

A method for taking samples of the gut or intestinal tract using a capsule device, the method comprising:

• providing a capsule device configured to be swallowed and passed through the intestinal tract of the patient, wherein the capsule device comprising:
• a housing comprising an aperture used to collect a sample, wherein within the housing a specific chemical substance or protein has been placed;
• and
• at least one motor and actuator within the housing;
• and
• actuating the device at a specific time, wherein the actuating causes the aperture to be opened for a period of time, wherein during the period of time that the aperture is opened, samples of the gut or intestinal tract are capable of entering a chamber area of the device where the specific chemical substance or protein has been placed,
• wherein, once the period of time has elapsed, the aperture is closed and sealed preserving the samples of the gut or intestinal tract entered.