Method for determining vitamin b12 uptake
AssigneeNestec S.A.
InventorsJerome Feige, Alice Pannerec
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Abstract
The present invention relates to a method for determining a level of intestinal uptake of vitamin B12 in a subject comprising: —determining a level of the cubam complex or a component thereof in an isolated sample from the subject; and —comparing the level of the cubam complex or a component thereof to reference levels; wherein the level of the cubam complex or a component thereof compared to the reference levels is indicative of the level intestinal uptake of vitamin B12.
Claims30
A method for determining a level of intestinal uptake of vitamin B12 in a subject comprising:
- determining a level of the cubam complex or a component thereof in an isolated sample from the subject;
- and
- comparing the level of the cubam complex or a component thereof to reference levels;
- wherein the level of the cubam complex or a component thereof compared to the reference levels is indicative of the level of intestinal uptake of vitamin B12.
A method for determining if a subject has impaired intestinal uptake of vitamin B12 comprising:
- determining a level of the cubam complex or a component thereof in an isolated sample from the subject;
- and
- comparing the level of the cubam complex or a component thereof to reference levels;
- wherein the level of the cubam complex or a component thereof compared to the reference levels is indicative of impaired intestinal uptake of vitamin B12.
Use of the cubam complex or a component thereof as a biomarker for the level of intestinal uptake of vitamin B12.
An antibody which is capable of specifically binding to the cubam complex or a component thereof or a degradation product thereof.
Dependencies are inferred from the claim text.