Micropatterning technique for creating morphologically specific free-floating structures for use as Standards in the pharmaceutical industry

A micropatterning method for creating morphologically specific free-floating structures for use as Standards in the pharmaceutical industry to test objects in drug containers, comprising:

• (a) micropatterning morphologically specific free-floating structures, wherein the micropatterning comprises:
• (i) providing a substrate;
• (ii) depositing a layer of UV light sensitive material onto the substrate;
• (iii) exposing the wafer to UV light underneath a photomask with a desired pattern and specific morphologic dimensions defined by the desired pattern to remove areas exposed to the UV light and leaving the desired pattern of the UV light material on the substrate;
• (iv) coating the substrate and the desired pattern of the UV light material left on the substrate with a coating layer wherein the thickness of the coating does not exceed the thickness of the UV light sensitive layer;
• and
• (v) using a solvent to lift-off structures of the coating layer which are defined by the desired pattern, wherein the lifted-off structures are referred to as standards;
• (b) providing a container filled a defined number of the standards;
• and
• (c) using the filled container as a standard for testing other drug products held in a drug container, wherein the testing pertains to optically identifying structures in the drug container (j) similar in size and shape as the standards, or (jj) different in size and shape as the standards.

A method of using morphologically specific free-floating structures as Standards in the pharmaceutical industry to test objects in drug containers, comprising:

• (a) micropatterning morphologically specific free-floating structures defined by a desired pattern, wherein structures are referred to as standards;
• (b) providing a container filled a defined number of the standards;
• and
• (c) using the filled container as a standard for testing other drug products held in a drug container, wherein the testing pertains to optically identifying structures in the drug container (j) similar in size and shape as the standards, or (jj) different in size and shape as the standards.