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AssigneeFraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.
InventorsRolf Fendel, Stephanie Kapelski, Stefan Barth, Rainer Fischer, Andreas Reimann
Estimating the term…
The technology provided herein relates to novel anti-parasitic complexes, in particular recombinant fusion proteins suitable as human and/or animal drugs against a parasite of the phylum Apicomplexa, in particular against Plasmodium falciparum (P. falciparum) comprising at least one component A and at least one component B, characterized in that component A has a binding activity for cellular surface structures presented on the surface of a parasite of the phylum Apicomplexa or for parasitic antigens presented on a parasitized host cell, and component B is a compound having anti-parasitic activity.
A complex comprising at least one component A and at least one component B, characterized in that component A has a binding activity either for cellular surface structures presented on the surface of a parasite of the phylum Apicomplexa or for parasitic antigens presented on a parasitized host cell and component B is a compound having anti-parasitic activity, wherein the compound having anti-parasitic activity is wild type human granzyme B or a variant or a functional fragment thereof.
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Dependencies are inferred from the claim text.