Anitmicrobial peptide produced by intestinal lactobacillus salivarius
AssigneesUniversity College Cork, National University of Ireland, Cork, Agriculture and Food Development Authority (Teagasc)
InventorsPaul ROSS, Eileen O'SHEA, Colin HILL
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Abstract
An antimicrobial peptide having potent antibacterial activity against Listeria monocytogenes and Staphylococcus aureus is described. Also described is an isolated Lactobacillus salivarius DPC6502 strain as deposited with the National Collection of Industrial and Marine Bacteria under the Accession No. NCIMB 41840, and variants thereof, wherein the isolated bacteria and variants thereof express an antimicrobial peptide of the invention.
Claims12
-39. (canceled)
A method of treating or preventing growth of Listeria, Staphylococcus aureus or L. delbrueckii subsp. bulgaricus, or a disease or a condition characterised by the growth of Listeria, Staphylococcus aureus or L. delbrueckii subsp. bulgaricus comprising administering an isolated antimicrobial peptide of SEQ ID NO:
- 2, or a variant thereof having at least 90% sequence identity with SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.