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US 2017/0253597 A9Published application
Crystalline forms of pemetrexed diacid and manufacturing processes therefor
AssigneeScinoPharm Taiwan, Ltd.
InventorsYing-Tzu Lin, Kuan-Hsun Wang, Wei-Shuo Lo, Wen-Wei Lin, Wan-Yin Cheng
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Abstract
Crystalline forms of pemetrexed diacid are provided (Forms 1 and 2) which are readily produced for either laboratory-scale or industrial scale. Processes for the preparation of Forms 1 and 2 are also provided.
Claims15
A crystalline Form 1 of pemetrexed diacid, characterized by a powder X-ray diffraction pattern with peaks at about 13.3, 15.8, 21.2, 26.2 and 26.7±0.2 degrees two-theta.
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Dependencies are inferred from the claim text.