Peptide reagents and methods for detection and targeting of dysplasia, early cancer and cancer
AssigneeThe Regents of the University of Michigan
InventorsThomas D. Wang, Juan Zhou, Bishnu P. Joshi
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AssigneeThe Regents of the University of Michigan
InventorsThomas D. Wang, Juan Zhou, Bishnu P. Joshi
Estimating the term…
The present invention is directed to EGFR-specific peptide reagents, methods for detecting pre-cancer, early cancer and/or cancer using the peptide reagents, and methods for targeting pre-cancer cells, early cancer cells and/or cancer cells using the peptide reagents. In one aspect, the disclosure provides reagents consisting essentially of a peptide QRHKPRE (SEQ ID NO: 1), HAHRSWS (SEQ ID NO: 2), YLTMPTP (SEQ ID NO: 3), TYPISFM (SEQ ID NO: 4), KLPGWSG (SEQ ID NO: 5), IQSPHFF (SEQ ID NO: 6), YSIPKSS (SEQ ID NO: 7), SHRNRPRNTQPS (SEQ ID NO: 8), NRHKPREKTFTD (SEQ ID NO: 9).
A reagent consisting essentially of a peptide QRHKPRE (SEQ ID NO:
The reagent of 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 or 11 comprising a therapeutic moiety attached to the peptide.
A peptide consisting of the amino acid sequence QRHKPRE (SEQ ID NO:
Dependencies are inferred from the claim text.