Methods, devices, and systems for non-invasive delivery of microwave therapy

A system for treating a skin tissue of a patient comprising:

• a microwave energy generator, the microwave energy generator being configured to deliver microwave energy at a frequency of about 5.8 GHz;
• a microwave antenna configured for placement proximate to the skin tissue, the microwave antenna being a waveguide antenna comprising an array of waveguide antennas, the array of waveguide antennas being configured for simultaneous or sequential treatment of multiple sections of skin tissue and to radiate electromagnetic radiation in the lowest-order Transverse Electric modes;
• an active cooling element configured for placement in contact with the skin tissue;
• and
• a suction element configured for elevating the skin tissue and placing the skin tissue in contact with the cooling element;
• wherein the microwave antenna is operatively coupled to the microwave energy generator, and wherein the microwave antenna is configured to deliver energy to the skin tissue sufficient to create a thermal effect in a target tissue within a skin tissue.