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US 2016/0355892 A1Published application
Detecting neoplasm
AssigneeMayo Foundation for Medical Education and Research
InventorsDavid A. Ahlquist, John B. Kisiel, William R. Taylor, Tracy C. Yab, Douglas W. Mahoney
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Abstract
Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.
Claims1
A method of screening for a neoplasm in a sample obtained from a subject, the method comprising:
- 1) assaying a methylation state of a marker in a sample obtained from a subject;
- and
- 2) identifying the subject as having a neoplasm when the methylation state of the marker is different than a methylation state of the marker assayed in a subject that does not have a neoplasm,
- wherein the marker comprises a base in a differentially methylated region (DMR) selected from a group consisting of DMR 1-107.
1 more element
Dependencies are inferred from the claim text.