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US 2016/0355577 A1Published application
Methods and compositions for targeting polyubiquitin
AssigneeGenentech, Inc.
InventorsRobert F. Kelley, Marissa Matsumoto
Life of this patent
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Abstract
Anti-K63-linked polyubiquitin monoclonal antibodies, and methods for using the antibodies, are provided.
Claims21
An isolated antibody or antigen-binding fragment thereof that specifically binds to K63-linked polyubiquitin, comprising at least one hypervariable (HVR) sequence selected from HVR-H2 and HVR-L2 of any of SEQ ID NOs:
- 59-110 and 112, and 7-58 and 111, respectively.
-15. (canceled)
Dependencies are inferred from the claim text.