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US 2016/0355481 A1Published application
Type 4 prepilin peptidase inhibitors and methods of use
AssigneeTrustees of Dartmouth College
InventorsRonald K. Taylor, Gordon W. Gribble
Life of this patent
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Abstract
Compounds for inhibiting Type 4 Prepilin Peptidases are provided as are methods of using the compounds as an ti-bacterial agents.
Claims3
A compound having the structure of Formula I:
- wherein R is a hydrogen, hydroxyl group or a substituted or unsubstituted C1-C6 alkyl group, X is an organic or inorganic anion, and L is a linker having one of the following structures:
A method for preventing or treating a bacterial infection comprising administering to a subject in need of treatment an effective amount of the pharmaceutical composition comprising a compound having the structure of Formula I:
- wherein R is a hydrogen, hydroxyl group or a substituted or unsubstituted C1-C6 alkyl group, X is an organic or inorganic anion, and L is a linker having one of the following structures.
- thereby preventing or treating the subject's bacterial infection.
Dependencies are inferred from the claim text.