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US 2016/0355473 A1Published application
Beta-lactam cholesterol absorption inhibitors
AssigneeRudjer Boskovic Institute
InventorsIvan Habus, Tonko Drazic
Life of this patent
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Abstract
The present invention relates to the novel compounds represented by Formula (Ia) or (Ib) and to their pharmaceutical preparations for the treatment of atherosclerosis and cholesterol level reduction.
Claims21
A compound of Formula (Ia) or (Ib):
- wherein R represents
- a) hydrogen;
- b) —C(═O)—C1-6alkyl-C6H4R3, —C(═O)—C1-6alkenyl-C6H4R3 or —C(═O)—C6H4R3;
- c) —C1-6alkyl-C6H4R3 or —C1-6alkenyl-C6H4R3, wherein said —C1-6alkyl or —C1-6alkenyl is substituted by OH;
- R1 represents —OH or —OMe;
- R2 represents a halogen or —OMe;
- R3 represents hydrogen, a halogen, —OMe, —NO2 or —OH;
- or a salt thereof.
5 more elements
20-21. (canceled)
Dependencies are inferred from the claim text.