Fumarate compounds, pharmaceutical compositions thereof, and methods of use

A compound according to Formula (I):

• or a pharmaceutically acceptable salt thereof, wherein:
• each R1 and R2 is independently chosen from hydrogen, C1-6 alkyl, substituted C1-6 alkyl, C1-6 heteroalkyl, substituted C1-6 heteroalkyl, C3-12 cycloalkyl, substituted C3-12 cycloalkyl, C4-12 cycloalkylalkyl, substituted C4-12 cycloalkylalkyl, C6-10 aryl, substituted C6-10 aryl, C7-12 arylalkyl, and substituted C7-12 arylalkyl;
• or each R1 and R2 together with the nitrogen to which they are bonded independently forms a ring chosen from a C3-12 heterocycloalkyl, substituted C3-12 heterocycloalkyl, C5-10 heteroaryl, and substituted C5-10 heteroaryl;
• and
• each R3 and R4 is independently chosen from hydrogen, C1-6 alkyl, and substituted C1-6 alkyl;
• wherein each substituent group is independently chosen from halogen, —OH, —CN, —CF3, ═O, —NO2, benzyl, —C(O)NR212, —R21, —OR21, —C(O)R21, —C(O)OR21, —NR212, —NR21C(O)R21, and —O(O)R21, wherein each R21 is independently chosen from hydrogen and C1-4 alkyl.