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US 2016/0354579 A1Published application
Body lumen fluid delivery device
AssigneeAtrium Medical Corporation
InventorsSteve A. HERWECK, Ronit R. FURMAN
Life of this patent
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AssigneeAtrium Medical Corporation
InventorsSteve A. HERWECK, Ronit R. FURMAN
Estimating the term…
A method and apparatus for fluid delivery enables navigation through tortuous, spatially restricted body anatomy to access narrow diameter body lumens for the continuous delivery of fluids, including therapeutic fluids, to the lumen in an atraumatic manner that avoids damage to the body lumen. The fluid delivery device can have a flexible conduit having a proximal end, a distal end, and a lumen extending along an interior of the flexible conduit providing a fluid flow path between the proximal and distal ends, where the lumen transitions into a micro-lumen exiting through a port through which a high concentration of fluid injected into the lumen exits laterally out along an image viewable zone at the distal end of the flexible conduit. The flexible conduit has a maximum outer diameter sized sufficient to navigate narrow diameter body lumens.
1-16. (canceled)
The fluid delivery device of claim 51, further comprising one or more markers viewable in vivo by an imaging device, the one or more markers comprised of heavy radiopaque metal component materials;
The fluid delivery device of claim 51, wherein fluid flowing through the fluid flow path exits the port into a target body location at a rate insufficient to damage tissue.
The fluid delivery device of claim 51, wherein if a fluid having a viscosity of 1 cps at 25° C. is supplied to the flexible conduit at a pressure of between about 1 atmosphere and about 4 atmospheres, a flowrate through the flexible conduit does not exceed 17 cc/min.
The fluid delivery device of claim 51, wherein if a fluid having a viscosity of 5 cps at 25° C. is supplied to the flexible conduit at a pressure of between about 1 atmosphere and about 4 atmospheres, a flowrate through the flexible conduit does not exceed 4 cc/min.
The fluid delivery device of claim 51, wherein if a fluid having a viscosity of 11 cps at 25° C. is supplied to the flexible conduit at a pressure of between about 1 atmosphere and about 4 atmospheres, a flowrate through the flexible conduit does not exceed 2 cc/min.
(canceled)
The fluid delivery device of claim 51, wherein the flexible conduit has a hydrophilic exterior surface.
The fluid delivery device of claim 51, wherein the flexible conduit has a hydrophobic exterior surface.
The fluid delivery device of claim 51, further comprising a coating disposed on an exterior surface of the flexible conduit.
The fluid delivery device of claim 51, wherein the fluid comprises a medication, a therapeutic agent, a diagnostic agent, or any combination thereof.
The fluid delivery device of claim 51, wherein the fluid comprises an emulsion, a nanoemulsion, or a cellular suspension comprised of cellular, genetic or viral material.
The fluid delivery device of claim 51, wherein the fluid comprises at least one of antioxidants, anti-hypertensive agents, anti-inflammatory agents, anti-infective agents, antibiotic agents, growth factor antagonists, anti-platelet agents, anti-coagulant agents, thrombolytic agents, drugs to alter lipid metabolism, ACE inhibitors, anti-proliferatives, anti-neoplastics, tissue growth stimulants, gasses, agents for promotion of hollow organ occlusion or thrombosis, agents for functional protein or factor delivery, agents for second messenger targeting, angiogenic agents, anti-angiogenic agents, agents for gene delivery, agents for local tissue perfusion, nitric oxide donating derivatives, thrombus-inducing agents, vasodilators, neuroprotective agents, neuronal healing agents, saline, and contrast media.
32-50. (canceled)
A fluid delivery device for treating a body lumen or cavity, comprising:
Dependencies are inferred from the claim text.