Drug-eluting device for prophylaxis or treatment of a disease or pathology
AssigneeFluid Biotech Inc.
InventorsALIM P. MITHA, JOHN H. WONG, PALLAVI BHAMBRI
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Abstract
The invention disclosed herein generally relates to particular intravascular drug-eluting delivery devices and methods for manufacture and use in either the prophylaxis or treatment of a disease or pathology. In one aspect, the intravascular device may comprise a verapamil eluting stent with polymeric coating designed for the controlled release of a vasodilating drug in the prophylactic or remedial treatment of cerebral vasospasm.
Claims37
A drug eluting prosthesis for the controlled release of one or more drugs in the remedial or prophylactic treatment of a disease, the prosthesis comprising:
- a prosthesis body having an inner surface and an outer surface;
- at least one layer of biodegradable polymeric material bonded to at least one surface of the prosthesis body, the polymeric material being capable of absorbing and releasing the one or more drugs;
- at least one drug dispersed within at least one layer of the polymeric material;
- wherein the controlled release comprises control over initiation time for drug elution, control over duration time for drug elution, and control over quantity of drug being eluted.
A verapamil eluting stent for the controlled delivery of verapamil in the prophylactic or remedial treatment of cerebral vasospasm, the stent comprising:
- a stent body having a lumen with a diameter, an inner surface and an outer surface. at least one layer of biodegradable polymeric material bonded to at least one surface of the stent body;
- verapamil dispersed within at least one layer of the polymeric material;
- wherein the controlled delivery of verapamil comprises control over initiation time for verapamil elution, control over duration time for verapamil elution, and control over quantity of verapamil being eluted.
Use of a drug eluting prosthesis for the controlled release of one or more drugs in the remedial or prophylactic treatment of a disease, the prosthesis comprising a prosthesis body having an inner surface and an outer surface, at least one layer of polymeric material bonded to at least one surface of the prosthesis body, at least one drug dispersed within at least one layer of the polymeric material, wherein the controlled release comprises control over initiation time for drug elution, control over duration time for drug elution, and control over quantity of drug being eluted.
Use of a verapamil eluting prosthesis for the controlled delivery of verapamil in the prophylactic or remedial treatment of cerebral vasospasm, the prosthesis comprising a prosthesis body having an inner surface and an outer surface, at least one layer of biodegradable polymeric material bonded to at least one surface of the prosthesis body, verapamil dispersed within at least one layer of the polymeric material;
- wherein the controlled delivery of verapamil comprises control over initiation time for verapamil elution, control over duration time for verapamil elution, and control over quantity of verapamil being eluted.
Dependencies are inferred from the claim text.