Back to results
US 2016/0354499 A1Published application
Radio-imaging and radio-therapy of cancer using antibodies to haah
AssigneePanacea Pharmaceuticals, Inc.
InventorsHossein A. GHANBARI, Steven Andrew FULLER
Life of this patent
Estimating the term…
Abstract
The present invention is directed to compositions and method for providing radio-imaging and radiotherapy for cancer. In particular, methods for making and using radio-labeled anti-HAAH antibodies for tumor imaging and immunotherapy are provided.
Claims16
A method for killing cancer cells, comprising the steps of:
- conjugating a radioisotope to an antibody which binds to human aspartyl (asparaginyl) β-hydroxylase (HAAH) to form a radiolabeled antibody and contacting cancer cells with the radiolabeled antibody which binds to HAAH, thereby killing the cancer cells.
A method for treating cancerous tissue in a mammal, comprising the steps of:
- conjugating a radioisotope to an antibody which binds to human aspartyl (asparaginyl) β-hydroxylase (HAAH) to form a radiolabeled antibody and contacting cancerous tissue of said mammal with the radiolabeled antibody which binds to HAAH.
A radioimmunoconjugate comprising a chelating agent, a radioisotope, and a fully human anti-HAAH antibody.
Dependencies are inferred from the claim text.