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US 2016/0354476 A1Published application
Targeted therapeutic nucleosides and their use
AssigneeIonis Pharmaceuticals, Inc.
InventorsPunit P. Seth, Thazha P. Prakash
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Abstract
Provided herein are compounds comprising one or more therapeutic nucleosides and one or more targeting groups. In certain embodiments, the compounds further comprise one or more oligonucleotides. In certain embodiments, a targeting group comprises one or more N-Acetylgalactosamine.
Claims21
1-235. (canceled)
A compound comprising a targeting group and at least one therapeutic nucleoside, wherein the targeting group comprises at least one cell-targeting ligand.
Dependencies are inferred from the claim text.