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US 2016/0354473 A1Published application
Cosmetic and Pharmaceutical Foam
AssigneeFoamix Pharmaceuticals Ltd.
InventorsDov Tamarkin, Doron Friedman, Meir Eini
Life of this patent
Estimating the term…
Abstract
The invention relates to an alcohol-free cosmetic or pharmaceutical foam carrier comprising water, a hydrophobic solvent, a foam adjuvant agent, a surface-active agent and a water gelling agent. The cosmetic or pharmaceutical foam carrier does not contain aliphatic alcohols, making it non-irritating and non-drying. The alcohol-free foam carrier is suitable for inclusion of both water-soluble and oil soluble pharmaceutical and cosmetic agents.
Claims23
(canceled)
A foamable pharmaceutical or cosmetic carrier suitable for topical or mucosal administration, comprising:
- (a) a foamable emulsion composition comprising:
- about 5% to about 75% by weight of the composition of a liquid, hydrophobic solvent comprising a volatile silicone oil and an emollient, wherein the volatile silicone oil is in an amount of at least 2% by weight of the composition;
- about 25% to about 95% by weight of the composition of water;
- about 0.1% to about 5% by weight of the composition of a foam adjuvant agent selected from the group consisting of cetyl alcohol, stearyl alcohol, arachidyl alcohol, behenyl alcohol, 1-triacontanol (C30), a fatty alcohol having a carbon chain comprising between 31 and 50 carbon atoms, a fatty alcohol derived from beeswax, erucyl alcohol, tetracosanol, hexacosanol, heptacosanol, octacosanol, triacontanol, hexadecanoic acid, stearic acid, arachidic acid, behenic acid, octacosanoic acid, a fatty acid having a carbon chain comprising between 30 and 50 carbon atoms, 12-hydroxy stearic acid, and mixtures of any two or more thereof;
- about 0.1% to about 5% by weight of the composition of a surface active agent, wherein said surface active agent comprises a non-ionic surface active agent, or a mixture of a non-ionic surfactant and an ionic surfactant wherein the ratio of the non-ionic surface active agent to the ionic surface active agent is greater than 6:1;
- and
- about 0.1% to about 5% by weight of the composition of a water gelling agent selected from the group consisting of a naturally-occurring polymeric material, a starch, a chemically modified starch, a cellulose ether, a guar gum, a chemically modified guar gum, soluble starch, a cationic cellulose, and mixtures of any two or more thereof;
- and
- (b) a liquefied or compressed gas propellant selected from the group consisting of a hydrocarbon propellant, a fluorocarbon propellant, and mixtures thereof;
- wherein the emulsion composition includes less than about 7.5% by weight of short chain aliphatic alcohols;
- wherein the carrier is housed in a container, and upon release from the container the carrier forms a breakable foam that collapses upon application of shear force;
- and
- wherein the combined amount of foam adjuvant agent, surface active agent, and water gelling agent is less than about 8% (w/w).
10 more elements
Dependencies are inferred from the claim text.