Nerve modulation systems

A system for generating a path to a target treatment site within bone, the system comprising:

• a cannula;
• a first stylet;
• and
• a radiofrequency (“RF”) energy delivery device configured to deliver energy to the target treatment site,
• wherein the cannula comprises an internal passageway and a first alignment member at a proximal portion of the cannula,
• wherein the cannula and the first stylet are together configured to form a first path toward the target treatment site within a cancellous region of the bone;
• wherein a second stylet is configured to be inserted within the internal passageway of the cannula upon removal of the first stylet,
• wherein a distal end portion of the second stylet is configured to be advanced out of an open distal tip of the cannula to form a second path beyond the first path,
• wherein the RF energy delivery device is configured to be inserted within the internal passageway of the cannula upon removal of the second stylet, and
• wherein the energy delivered by the RF energy delivery device is configured to heat the target treatment site sufficient to denervate a nerve within the bone.

A system for generating a path to a target treatment location within bone, the system comprising:

• an energy delivery device configured to deliver energy to heat the target treatment location;
• a cannula having an internal passageway and an opening at a distal tip of the cannula;
• a stylet sized to be advanced through the internal passageway until a distal tip of the stylet extends to or beyond the opening at the distal tip of the cannula, thereby facilitating formation of a first path within the bone as the cannula and stylet are advanced toward the target treatment location within the bone;
• wherein, after removal of the stylet, the energy delivery device is sized and configured to be advanced through the internal passageway and out of the opening at the distal tip of the cannula in a linear direction to the target treatment location beyond the first path formed by the cannula,
• wherein a diameter of the internal passageway of the cannula is configured to receive the energy delivery device, and
• wherein the energy is configured to heat the target treatment location sufficient to denervate a nerve at the target treatment location.

A system for generating a path to a target region within bone, the system comprising

• a cannula, wherein the cannula comprises an internal passageway and a first alignment member at a proximal portion of the cannula;
• a stylet, wherein the stylet comprises a second alignment member configured to be aligned with the first alignment member of the cannula to facilitate proper alignment of the cannula and the stylet,
• wherein the cannula and the stylet are configured to together form a channel toward the target region within the bone;
• and
• a treatment device sized and configured to be delivered through the cannula and advanced out of an open distal tip of the cannula in a linear direction beyond the channel formed by the cannula and the stylet.