US 2016/0260210 A1Published application

Method and system for determining the prognosis of a patient suffering from pulmonary embolism

AssigneesUniversidad Politecnica De Madrid, Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.

InventorsGermán SERRANO GONZÁLEZ, Daniel CARRETERO JIMÉNEZ, Frank JOHN RYBICKI, María J. LEDESMA CARBAYO, Sara LÓPEZ RODRÍGUEZ, Raúl ESTÉPAR SAN JOSÉ

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Abstract

A system for determining the prognosis of a patient suffering from pulmonary embolism is provided. The system may include at least one computer system configure to receive patient specific data regarding his pulmonary embolism status. The at least one computer system may be further configured to create a model of the patient's heart, with at least information of the two ventricles, and to determine the ratio of sizes of the ventricles. The system will then report such ratio to the clinician or report a risk index of clinical outcome for such patient.

Claims20

Dependent claims

A method for computing the Right Ventricle:Left Ventricle diameter ratio in a subject, the method comprising:

receiving a plurality of axial images of the patient showing at least the heart, forming a three-dimensional image formed by voxels;
automatically estimating, via a computer system, in at least one three-dimensional image the location and shape of the contour of the ventricles of the heart of the patient;
automatically estimating, via a computer system, in at least one three-dimensional image the location of the inter-ventricular septum of the heart of the patient modeled as a plane;
automatically estimating, via a computer system, the diameter of the ventricles of the heart as the maximum width of the contour of each ventricle measured in lines perpendicular to the interventricular septum;
reporting the value of the division of the maximum measurement for a right ventricle to a maximum measurement for a left ventricle.

2 more elements

A computer-readable medium storing code, which when executed by a processor, causes the processor:

to receive a plurality of axial images of the patient showing at least the heart, forming a three-dimensional image formed by voxels;
to automatically estimating, via a computer system, in at least one three-dimensional image, the location and shape of the contour of the ventricles of the heart of the patient;
to automatically estimating, via a computer system, in at least one three-dimensional image, the location of the inter-ventricular septum of the heart of the patient modeled as a plane;
to automatically estimating, via a computer system, the diameter of the ventricles of the heart as the maximum width of the contour of each ventricle measured in lines perpendicular to the interventricular septum;
and
to report the value of the division of the maximum measurement for a right ventricle to a maximum measurement for a left ventricle.

3 more elements

An electronic device for data analysis, the device comprising

a processor;
and
a computer-readable medium storing computer-executable instructions which, when executed by the processor, causes the processor:
to receive a plurality of axial images of the patient showing at least the heart, forming a three-dimensional image formed by voxels;
to automatically estimating, via a computer system, in at least one three-dimensional image, the location and shape of the contour of the ventricles of the heart of the patient;
to automatically estimating, via a computer system, in at least one three-dimensional image, the location of the inter-ventricular septum of the heart of the patient modeled as a plane;
to automatically estimating, via a computer system, the diameter of the ventricles of the heart as the maximum width of the contour of each ventricle measured in lines perpendicular to the interventricular septum;
and
to report the value of the division of the maximum measurement for a right ventricle to a maximum measurement for a left ventricle.

6 more elements

Dependencies are inferred from the claim text.

Facts

Application: 15/026,401Filed 27 Nov 2014
Priority: 27 Nov 2013
Published: 8 Sep 2016
Term ends: Not estimatedThe source records don’t support an estimate.

Classification28 codes

G06T 7/0012
Inspection of images, e.g. flaw detection: biomedical image inspection
A61B 5/7271
Signal processing specially adapted for physiological signals or for diagnostic purposes: specific aspects of physiological measurement analysis
G06F 18/217
Design or setup of recognition systems or techniques; Extraction of features in feature space; Blind source separation: validation; Performance…
G06F 18/22
Analysing: matching criteria, e.g. proximity measures

Family

Application61/909,574Us provisional application · filed 27 Nov 2013
US 9,905,002 B2Related patent
US 2016/0260210 A1This patent

From the US filing history. Foreign family members aren’t listed.

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