Method of monitoring live cells
AssigneeBiocompatibles UK Limited
InventorGiuseppe BATTAGLIA
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Abstract
The present invention relates to a method of monitoring live cells, comprising the sequential steps of: (i) contacting the cells with self-assembled constructs associated with an imaging agent at t=0; (ii) incubating the cells for a period of time t1; (iii) imaging at least a sample of the live cells by means of the said imaging agent after time t1; wherein in step (i), at least some of the constructs are taken up into the cells; and wherein the constructs comprise an amphiphilic block copolymer having a hydrophilic and hydrophobic block.
Claims23
A method of monitoring live cells, comprising the sequential steps of:
- (i) contacting the cells with self-assembled constructs associated with an imaging agent at t=0;
- (ii) incubating the cells for a period of time t1;
- (iii) imaging at least a sample of the live cells by means of the said imaging agent after time t1;
- wherein in step (i), at least some of the constructs are taken up into the cells;
- and wherein the constructs comprise an amphiphilic block copolymer having a hydrophilic and a hydrophobic block.
A composition comprising self-assembled constructs, and associated with the constructs, an imaging agent, wherein the constructs comprise an amphiphilic block copolymer having a hydrophilic and a hydrophobic block,
- and wherein the imaging agent is a biomolecule, or derived from a biomolecule, and is capable of targeting a specific cellular structure.
Dependencies are inferred from the claim text.