Multifunctional metal nanostructure and method for producing same
AssigneesImra America, Inc., Japanese Foundation for Cancer Research
InventorsYuki ICHIKAWA, Kiyotaka SHIBA
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Abstract
Provide is a stable metallic nanostructure that causes no aggregation when surface-modified with biomolecule-reactive functional molecules. 30 to 90% of the surface of the metallic nanostructure is covered with at least one or more types of colloid-stabilizing functional molecules. Furthermore, the metallic nanostructure is covered with one or more types of biologically functional molecules.
Claims17
A multifunctional metallic nanostructure comprising a metallic nanostructure having a surface covered with:
- at least one or more types of colloid-stabilizing functional molecules which cover 30 to 90% of the surface of the metallic nanostructure;
- and
- at least one or more types of biologically functional molecules having a terminal amino acid.
A method for manufacturing a multifunctional metallic nanostructure, comprising the steps of:
- providing a metallic nanostructure dispersed in water or an electrolyte solution;
- covering 30 to 90% of a surface of the metallic nanostructure with colloid-stabilizing functional molecules, by monitoring an amount of surface covering of the metallic nanostructure with measurement of a physical quantity;
- and
- covering the surface of the metallic nanostructure with one or more types of biologically functional molecules.
Dependencies are inferred from the claim text.