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US 2016/0258853 A1Published application
Method for Determining Volume and Hemoglobin Content of Individual Red Blood Cells
AssigneeAbbott Laboratories
InventorsGiacomo Vacca, Martin Krockenberger, Diana Garrett
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Abstract
Provided herein is a method for determining the volume or hemoglobin content of an individual red blood cell in a sample containing a population of red blood cells. The method may be performed on a hematology analyzer. Also provided are a hematology analyzer for performing the method and a computer-readable medium containing programming for performing the method.
Claims21
1-20. (canceled)
A method for calculating a volume, a hemoglobin content, or both, of a red blood cell in a blood sample, the method comprising:
- passing a blood sample through a flow cell of a hematology analyzer;
- directing light to the flow cell from a light source;
- generating optical data using one or more optical detectors for detecting optical characteristics of the blood sample;
- measuring a hemoglobin concentration in the blood sample using a colorimetric transducer;
- measuring a change in impedance in the blood sample using an impedance transducer;
- and
- calculating a volume, a hemoglobin content, or both, of a red blood cell in the blood sample based on the optical data, the hemoglobin concentration, and the change in impedance.
4 more elements
Dependencies are inferred from the claim text.