US 2016/0257936 A1 · Method for Differentiating Pluripotent Stem Cell Induced from Mesenchymal Stem Cell into Chondrocyte

Abstract

The present invention relates to a medium composition containing an Ecklonia cava extract for dedifferentiating an induced pluripotent stem cell. Also, the present invention relates to a method for differentiating an induced pluripotent stem cell, produced by using the medium composition into a chondrocyte. When using the medium composition according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into chondrocytes.

Claims9

Dependent claims

A method for differentiating mesenchymal stem cells into chondrocyte, comprising the steps of:

(a) adding an Ecklonia cava extract to a cell culture medium;
(b) dedifferentiating mesenchymal stem cells into induced pluripotent stem cells in the medium;
and
(c) differentiating the induced pluripotent stem cells into chondrocytes.

1 more element

Dependencies are inferred from the claim text.

Facts

Application

15/033,358Filed 5 Nov 2013

Priority

KR 10-2013-01320551 Nov 2013

Published

8 Sep 2016

Term ends

Not estimatedThe source records don’t support an estimate.

Classification11 codes

C12N 5/0655
Cells of skeletal and connective tissues; Mesenchyme: chondrocytes; Cartilage
A61P 19/00
Drugs for skeletal disorders
A61P 19/08
Drugs for skeletal disorders: for bone diseases, e.g. rachitism, Paget's disease
A61P 43/00
Drugs for specific purposes, not provided for in groups a61p1/00-a61p41/00

Method for Differentiating Pluripotent Stem Cell Induced from Mesenchymal Stem Cell into Chondrocyte

Life of this patent

Method for Differentiating Pluripotent Stem Cell Induced from Mesenchymal Stem Cell into Chondrocyte

Life of this patent

Abstract

Claims9