US 2016/0257935 A1 · Method for Differentiating Pluripotent Stem Cell Induced from Mesenchymal Stem Cell into Osteoblast

Abstract

The present invention relates to a medium composition containing an Ecklonia cava extract for dedifferentiation an induced pluripotent stem cell. Also, the present invention relates to a method for differentiating an induced pluripotent stem cell produced by using the medium composition into osteoblasts. When using the medium composition according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into osteoblasts.

Claims9

Dependent claims

A method for differentiating mesenchymal stem cells into osteoblasts, comprising the steps of:

(a) adding an Ecklonia cava extract to a cell culture medium;
(b) dedifferentiating mesenchymal stem cells into induced pluripotent stem cells in the medium;
and
(c) differentiating the induced pluripotent stem cells into osteoblasts.

1 more element

Dependencies are inferred from the claim text.

Facts

Application

15/033,393Filed 5 Nov 2013

Priority

KR 10-2013-01320571 Nov 2013

Published

8 Sep 2016

Term ends

Not estimatedThe source records don’t support an estimate.

Classification15 codes

C12N 5/0654
Cells of skeletal and connective tissues; Mesenchyme: osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
A61K 35/32
Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically…:…
A61P 19/00
Drugs for skeletal disorders
C12N 5/0696
Vertebrate cells: artificially induced pluripotent stem cells, e.g. iPS

Method for Differentiating Pluripotent Stem Cell Induced from Mesenchymal Stem Cell into Osteoblast

Life of this patent

Method for Differentiating Pluripotent Stem Cell Induced from Mesenchymal Stem Cell into Osteoblast

Life of this patent

Abstract

Claims9