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US 2016/0257756 A1Published application
Antibodies against ccr9 and applications thereof
AssigneeConsejo Superior de Investigaciones Cientificas
InventorsSonia CHAMORRO PÉREZ, Ana FRANCO VILLANUEVA, José Alberto GARCÍA SANZ, Leonor KREMER BARÓN, Carlos MARTÍNEZ ALONSO, María VELA CUENCA, Laura CARRAMOLINO FITERA
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Abstract
The present invention relates to antibodies binding specifically to CCR9, and to antigen-binding fragments thereof. It also relates to uses thereof and diagnostic methods using said antibodies.
Claims22
An antibody binding specifically to CCR9, or an antigen-binding fragment thereof, comprising
- a) a heavy chain comprising at least one complementarity determining region (CDR) selected from:
- a CDR comprising the amino acid sequence shown in SEQ ID NO:
- 1 [CDR-H1] or a variant thereof;
- a CDR comprising the amino acid sequence shown in SEQ ID NO:
- 2 [CDR-H2] or a variant thereof;
- and
- a CDR comprising the amino acid sequence shown in SEQ ID NO:
- 3 [CDR-H3] or a variant thereof;
- and
- b) a light chain comprising at least one complementarity determining region (CDR) selected from:
- a CDR comprising the amino acid sequence shown in SEQ ID NO:
- 4 [CDR-L1] or a variant thereof;
- a CDR comprising the amino acid sequence shown in SEQ ID NO:
- 5 [CDR-L2] or a variant thereof;
- and
- a CDR comprising the amino acid sequence shown in SEQ ID NO:
- 6 [CDR-L3] or a variant thereof.
14 more elements
Dependencies are inferred from the claim text.