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US 2016/0257694 A1Published application
Oridonin functionalized selenium nanoparticles and method of preparation thereof
AssigneeMacau University of Science and Technology
InventorsJiang PI, Jiye CAI, Hua JIN
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Abstract
The present invention relates to an oridonin functionalized selenium nanoparticle, method of preparing and use thereof for anti-cancer and anti-inflammatory treatments. The present invention provides oridonin functionalized selenium nanoparticle that is stable, water soluble and storable.
Claims8
A method of preparing oridonin functionalized selenium nanoparticle comprises:
- a) Providing a solution of selenium-containing compound, a solution of oridonin, a solution of reducing agent and a solution of stabilizer;
- b) Mixing the solutions of selenium-containing compound, oridonin, and stabilizer to form a first mixture;
- c) Adding the solution of reducing agent to the first mixture to form the nanoparticle,
- wherein the oridonin functionalized selenium nanoparticle comprises 0.01-10 mM selenium, 0.01-10 mM oridonin, 0.001%-10% stabilizer and 0.1-100 mM reducing agent.
1 more element
Dependencies are inferred from the claim text.