Inhibitors of human immunodeficiency virus replication

A compound of Formula I, including pharmaceutically acceptable salts thereof:

• wherein:
• R1 is alkyl, aryl, arylalkyl, cycloalkyl or heteroaryl;
• wherein said aryl, arylalkyl or heteroaryl moieties are linked to the parent molecule through their respective carbon atoms, and further wherein said R1 groups are substituted with 0-4 groups independently selected from the group of alkenyl, alkoxy, alkoxycarbonyl, alkoxycarbonylamino, alkyl, alkylsulphonyl, alkylthioxy, aminocarbonyl, alkynyl, carboxylic acid, cyano, halo, haloalkyl, haloalkoxy, hydroxy, hydroxyalkyl, thioxy, —SO2alkyl, heteroaryl, and nitro;
• R2 is —H, C1-C4 alkyl or C3-C4 cycloalkyl;
• or R1 and R2 together with the atoms to which they are attached form a heterocyclic ring optionally substituted with 0-2 alkyl groups;
• R3 is —H, C1-C4 alkyl or C3-C4 cycloalkyl;
• R4 is —H, alkyl, aryl, C5-C10 bicycloalkyl, cycloalkyl or heteroaryl which is substituted with 0-3 groups independently selected from the group of alkenoxy, alkenyl, alkoxy, alkoxycarbonyl, alkyl, benzyloxy, carboamide, cyano, halo, haloalkyl, haloalkoxy, —NHCO(alkyl), —SO2N-heterocycle, —OH, nitro, and —CH2OH;
• R5 and R6 are independently selected from H or alkyl, or R5 and R4 together with the atom to which they are attached form an aryl group, or R5 and R6 together with the atoms to which they are attached form a C3-C4 cycloalkyl;
• R7 is —H, alkyl, aryl, heteroaryl, heteroarylalkyl, C3-C7 cycloalkyl or dialkylaminoalkyl, wherein said aryl or heteroaryl is substituted with 0-3 groups independently selected from the group of —OH, —NHCOalkyl, —NHCON(alkyl)2, —NHCO2-alkyl, —CONH2, —CN, —SO2N(alkyl)2, alkoxy, alkyl, halo, haloalkoxy, and haloalkyl;
• and
• R8 is —H, alkyl, arylalkyl, cycloalkyl, haloalkyl or heteroarylalkyl;
• or R7 and R8 together with the nitrogen atom to which they are attached form a heterocycle which is substituted with 0-3 groups independently selected from the group of alkyl, alkoxy, halo, —OH, —CN, and —SO2N(alkyl)2.