Antimicrobial compounds

A compound of formula (I) for use in a method of treatment of a microbial infection in an animal:

• wherein:
• Q is selected from Q1, Q2, Q3, Q4, Q5 and Q6:
• n is 0 or 1;
• L is selected from —(CH2)m—, —C(═O)—, —(CH2)m—C(═O)—, —O—(CH2)m—C(═O)—, —O—C(═O)—(CH2)m—(C═O)—, —NH—C(═O)—, —NR—C(═O)—, —NH—(CH2)m—C(═O)—, —NR—(CH2)m—C(═O)—, —NH—C(═O)—(CH2)m—C(═O)—, —NR—C(═O)—(CH2)m—C(═O)—, —C(═O)—NH—(CH2)m—C(═O)—, and —(CH2)m—(CHRL)—C(═O)—, where m is an integer from 1 to 4;
• A1 and A2, together with the atoms to which they are bound, form an optionally substituted C6-14aryl group;
• A3, if present, is selected from H and optionally substituted C1-4alkyl;
• RN is selected from H and optionally substituted3 C1-4alkyl;
• one of B1, B2, B3, B4, and B5 is a group of formula —X—RX and the others are independently selected from H and RB;
• wherein each —RB is independently selected from halogen, —CF3, —R, —OH, —OR, —OCF3, —C(═O)OH, —C(═O)OR, —C(═O)R, —OC(═O)R, —NH2, —NHR, —NR2, —NO2, —C(═O)NH2, —C(═O)NHR, C(═O)NR2, —S(═O)R, —S(═O)2R, —S(═O)2NR2, or —CN;
• X is selected from a covalent bond or C1-3alkylene;
• RX is selected from —H, RXX or RXY;
• wherein:
• RXX is halogen, —CF3, —OH, —OR, —OCF3, —C(═O)OH, —NO2, —NH2, —NHR, —NR2,
• —C(═O)NH2,
• —C(═O)NR2, —S(═O)R, —S(═O)2R, —S(═O)2NR2, or —CN;
• and
• RXY is a group of formula -LX-RYY;
• wherein LX is selected from:
• —NH—C(═O)—O—, —NH—C(═O)—NH—, —NH—C(═O)—
• —O—C(═O)—NH—, —O—C(═O)—O—, —O—(C═O)—
• —C(═O)—NH—, —C(═O)—O—, —C(═O)—;
• and RYY is selected from C1-4alkyl, C3-6cycloalkyl, —C6-14aryl, -LY-C6-14aryl, -LY-O—C6-14aryl —C5-6heteroaryl, -LY-C5-6heteroaryl, and -LY-O—C5-6heteroaryl,
• wherein -LY- is C1-3alkylene and wherein each of said groups is optionally substituted;
• RL is selected from halogen, —RLL, —CF3, —OH, —ORLL, —NO2, —NH2, —NHRLL, —NR2, —NH—C(═O)—RLL, —NH—C(═O)—O—RLL wherein RLL is selected from —C1-4alkyl, —C3-6cycloalkyl, -Ph, -LL-Ph, —C5-6heteroaryl, -LL-C5-6heteroaryl wherein -LL- is C1-3alkylene.
• and wherein each R is independently C1-4alkyl.