Composition, method, system and kit for optical electrophysiology
AssigneesThe Research Foundation of State University of New York, University of Connecticut
InventorsArkady M. Pertsov, Arvydas Matiukas, Leslie M. Loew, Joseph P. Wuskell
Life of this patent
Estimating the term…
Abstract
The present invention provides a method of optical electrophysiological probing, including: providing a fluorescing chemical probe; contacting a thick portion of tissue with the fluorescing chemical probe to create a thick portion of treated tissue; applying a first range of wavelengths of electromagnetic radiation to the treated portion of tissue; and detecting a plurality of depth-specific emission wavelengths emitted from the thick portion of treated tissue.
Claims4
An optically mapping composition comprising a voltage-sensitive dye of the formula:
- wherein R1 is a first hydrocarbon group that is a butyl group;
- R2 is a second hydrocarbon group that is a butyl group;
- and R3 is a trimethylpropyl ammonium polar group.
Dependencies are inferred from the claim text.