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AssigneeProtiva Biotherapeutics, Inc.
InventorsJames HEYES, Lorne R. PALMER, Stephen P. REID, Edward D. YAWORSKI, Ian MACLACHLAN, Mark WOOD, Alan D. MARTIN
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The present invention provides compositions comprising mRNA molecules encapsulated within lipid particles. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions to ameliorate one or more symptoms of a disease. The invention also provided cationic lipids that are useful for preparing the compositions of the invention.
A lipid particle comprising a cationic trialkyl lipid, a non-cationic lipid, and an mRNA molecule that is encapsulated within the lipid particle.
Dependencies are inferred from the claim text.