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US 2016/0256557 A1Published application
Injectable pharmaceutical compositions of an anthracenedione derivative with anti-tumoral activity
AssigneeCti Biopharma Corp.
InventorsAlberto Bernareggi, Valeria Livi
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Abstract
Injectable pharmaceutical compositions containing 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione dimaleate as active ingredient in the form of a lyophilised powder with a carrier selected from lactose and dextran, mixed with sodium chloride.
Claims11
A pharmaceutical composition comprising 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione dimaleate and:
- i) a lactose carrier mixed with sodium chloride;
- or ii) a dextran carrier mixed with sodium chloride,
- wherein the composition is in the form of a lyophilized powder.
An aqueous composition comprising 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione dimaleate and:
- i) a lactose carrier mixed with sodium chloride;
- or ii) a dextran carrier mixed with sodium chloride,
- wherein the concentration of the 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione dimaleate in the composition ranges from 7-15 mg/ml.
Dependencies are inferred from the claim text.