Enhanced plasmonic nanoparticles for cancer therapy and diagnostics
AssigneeBoard of Supervisors of Louisiana State University and Agricultural and Mechanical College
InventorsLouis Hamilton Haber, Tony Eugene Karam, Holden Tyler Smith
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Abstract
One or more techniques and/or products are disclosed using a process for preparing metallic nanoparticles. Resulting nanoparticles may comprise a gold-silver-gold core-shell-shell nanoparticles. Such nanoparticles can be formed by forming a gold core, providing certain materials to form a silver shell, and providing certain materials to form a gold shell. The metallic nanoparticles may be used in molecular sensing, catalysis, photothermal therapy, and other biologically-relevant technologies.
Claims20
A process of preparing metallic nanoparticles comprising:
- adding a first citrate compound to a gold solution resulting in a gold core solution comprising at least one gold core;
- adding ascorbic acid, a silver compound, and a strong base to the gold core solution resulting in a silver shell on at least one gold core;
- and
- adding a second citrate compound, hydroquinone, and a gold compound to at least one silver shell on at least one gold core resulting in an outer gold shell on the silver shell.
A metallic nanoparticle made by the process of:
- adding a first citrate compound to a gold solution resulting in a gold core solution from comprising at least one gold core;
- adding ascorbic acid, a silver compound, and a strong base to the gold core solution resulting in a silver shell on at least one gold core;
- and
- adding a second citrate compound, hydroquinone, and a gold compound to at least one silver shell on at least one gold core resulting in an outer gold shell on the silver shell.
A metallic nanoparticle comprising:
- a gold core;
- a silver shell;
- and
- an outer gold shell.
Dependencies are inferred from the claim text.