Orally disintegrating tablet compositions of lamotrigine
AssigneeAdare Pharmaceuticals, Inc.
InventorsGopi M. Venkatesh, Nehal H. Vyas, Michael Gosselin, Jin-Wang Lai
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Abstract
The compositions of the present invention composition comprise a therapeutically effective amount of particles comprising lamotrigine, in combination with granules comprising a disintegrant, and a sugar alcohol and/or a saccharide. These compositions are useful in treating epilepsy and bipolar disorder, particularly for patients with dysphagia, and to improve compliance with bipolar patients.
Claims52
An orally dissolving or disintegrating (ODT) composition comprising a therapeutically effective amount of lamotrigine, wherein after administration said composition substantially disintegrates in the oral cavity of a patient and provides a lamotrigine release profile which is substantially the same as the lamotrigine release profile of an immediate release lamotrigine composition.
Dependencies are inferred from the claim text.