US 2016/0256428 A1 · COMPOSITION CONTAINING MONOACETYLDIACYLGLYCEROL COMPOUND AS ACTIVE INGREDIENT FOR INHIBITING BLOOD CANCER OR METASTASIS

Composition containing monoacetyldiacylglycerol compound as active ingredient for inhibiting blood cancer or metastasis

AssigneesEnzychem Lifesciences Corporation, Korea Research Institute of Bio Science and Biotechnology

InventorsJae Wha Kim, Sei Ryang Oh, Kyung Seop Ahn, Ho Bum Kang, Jae Min Shin, Young Eun Ko, Tae Suk Lee, Myung Hwan Kim, Jong Koo Kang, Yong-Hae Han, Ki-Young Sohn

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Abstract

The present invention relates to a composition containing a monoacetyldiglyceride compound as an active ingredient, for inhibiting blood cancer or metastasis, and a use thereof. The monoacetyldiglyceride compound according to the present invention has excellent effects of inhibiting the expression of IL-4 and inhibiting the activity of STAT-6, and thereby is capable of overcoming side effects of currently used blood cancer or metastasis inhibiting agents. Also, the monoacetyldiglyceride compound is a non-toxic compound having superior therapeutic effects and thus can be useful as a composition for preventing, treating, or improving blood cancer and metastasis.

Claims23

Dependent claims

A composition comprising a monoacetyldiacylglycerol compound of Formula 1 as an active ingredient for inhibiting blood cancer or cancer metastasis.

wherein R1 and R2 are independently a fatty acid group of 14 to 20 carbon atoms.

Dependencies are inferred from the claim text.

Facts

Application

14/912,916Filed 18 Aug 2014

Priority

KR 10-2013-009818519 Aug 2013

Published

8 Sep 2016

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Classification13 codes

A61K 31/231
Of acids having a carboxyl group bound to a chain of seven or more carbon atoms: having one or two double bonds
A23L 33/10
Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof: using additives
A61K 31/23
Of acyclic acids, e.g. pravastatin: of acids having a carboxyl group bound to a chain of seven or more carbon atoms
A61K 35/32
Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically…:…