Flexibly mounted cartridge alignment collar for drug delivery device

A method of supplying a drug to a delivery device comprising:

• compliantly supporting a collar including a cannula in a ready position on a frame of said drug delivery device;
• positioning a cartridge within a first deviation tolerance of a loaded position with respect to a frame;
• said positioning engaging an access channel of said cartridge to said collar when said cartridge is in said ready position;
• inserting an end of said cannula into said access channel;
• allowing movement of said collar with respect to said frame to comply with said loaded position of said cartridge to preserve an alignment of said end of said cannula with respect to said access channel to a second deviation tolerance less than said first deviation tolerance.

A method of preventing leakage from a cartridge of a drug delivery device comprising:

• providing a cartridge fitting supported on a housing of the delivery device and a cannula mounted to the fitting;
• piercing the septum with the cannula;
• rigidly engaging the fitting to the cartridge;
• allowing the fitting to move along with the cartridge with respect to the housing such that the cannula moves with the septum;
• wherein said moving of the cannula with the septum provides for inhibiting leaks caused by movement of the septum with respect to the cannula.