Integrated virtual patient framework

Abstract

An Integrated Virtual Patient Framework (IVPF) that incorporates dynamic and mechanistic modeling to provide for testing of finer patient-specific data subdivisions, and also allows non-standard therapies to be queried for success. New measurements of patient follow-up data can be rapidly incorporated into the IVPF in order to dynamically update the optimization of the treatment strategy, making the IVPF a powerful tool for implementing adaptive therapies. The IVPF is built using software is accessible to the nonmathematician. Inputs, options, and decision recommendations are delivered in a fashion that will have clear meaning to the clinician deciding the treatment. The system is adaptable to the different decision processes which are used in the clinic. Each disease has a particular decision set that the framework will be able to handle.

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