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AssigneesCalifornia Institute of Technology, University of Southern California
InventorsAmir Goldkorn, Yu-Chong Tai, Tong Xu, Bo Lu
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The present invention provides a method for diagnosing cancer, predicting a disease outcome or response to therapy in a patient sample. The method involves isolating a circulating tumor cell (CTC), for example, a viable CTC, from a sample using a parylene microfilter device comprising a membrane filter having or consisting of a parylene substrate, which has an array of holes with a predetermined shape and size; and detecting and quantifying telomerase activity in blood circulating tumor cells. The invention further provides methods of using cells live-captured in various applications.
-17. (canceled)
A method for detecting and quantifying the telomerase activity of a circulating tumor cell, said method comprising:
-41. (canceled)
A method for staining a circulating tumor cell (CTC), said method comprising:
(canceled)
A method for measuring telomerase activity in a single circulating tumor cell (CTC), said method comprising:
Dependencies are inferred from the claim text.