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US 2016/0251306 A1Published application
Dimethylbenzoic acid compounds
AssigneeEli Lilly and Company
InventorsMaria Jesus Blanco-Pillado, Peter Rudolph Manninen, Matthew Allen Schiffler, Tatiana Natali Vetman, Alan M Warshawsky, Jeremy Schulenburg York
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Abstract
The present invention provides a compound of the Formula I: wherein A is: and W, Y, X, R1, R2, R3, and R4 are as defined herein, or a pharmaceutically acceptable salt thereof, for use as an inhibitor of the EP4 receptor.
Claims19
A compound of the formula:
- wherein A is:
- W is CH or N;
- Y is CH or N;
- X is CH or N;
- R1 is CH3, CF3, or F;
- R2 is H, F, Cl, CH3, CF3, CH2OH, CH2CH2OH, CH2OCH3, OCH3, OCF3, or CN;
- R3 is H or F;
- or
- R2 and R3 together are a OCH2O group attached to vicinal carbon atoms;
- R4 is H, Cl, or CH2OH;
- or a pharmaceutically acceptable salt thereof.
8 more elements
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Dependencies are inferred from the claim text.