An inhalable medicament
AssigneeTeva Branded Pharmaceutical Products R&D, Inc.
InventorsMukul Dalvi, Libo Wu
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Abstract
Accordingly, the present invention provides a solution formulation for inhalation comprising: a liquid phase; an active ingredient having a functional group which is susceptible to hydrolysis and/or solvolysis, dissolved in the liquid phase; and a magnesium or calcium salt, dissolved in the liquid phase. The formulation is particularly suited to pMDIs and nebulisers.
Claims25
A solution formulation for inhalation comprising:
- a liquid phase;
- an active ingredient having a functional group which is susceptible to hydrolysis and/or solvolysis, dissolved in the liquid phase;
- and
- at least one of a magnesium or calcium salt, dissolved in the liquid phase.
A method of stabilizing an active ingredient having a functional group which is susceptible to hydrolysis and/or solvolysis, wherein the active ingredient is present in a solution formulation for inhalation, the method comprising formulating the solution formulation using at least one of a magnesium salt or a calcium salt.
Dependencies are inferred from the claim text.